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TMS Therapy VS ECT: What’s The Difference And When Should ECT NOT Be Used?

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Transcranial Magnetic Stimulation (TMS) and Electroconvulsive Therapy (ECT) are two different mental health therapies that have garnered attention for their effectiveness in treating mood disorders, especially major depressive disorder (MDD). Because both therapies use electric pulses to activate the natural electro-chemical activity of the brain, they often invite comparison and can sometimes be confused with each other. Nonetheless, TMS and ECT are completely different procedures in terms of their mechanisms, side effects, and applications. Is TMS or ECT right for you? This article looks at TMS therapy versus ECT and answers some common questions about the benefits and drawbacks of each.

What’s The Difference Between TMS and ECT?

TMS employs repetitive magnetic pulses to the brain area associated with mood disorders, e.g., the prefrontal cortex in the case of depression. The pulses stimulate the activity of the neurons inside the brain in a way that can alleviate a patient’s symptoms. TMS is noninvasive and administered via a head-mounted device similar to a bathing cap. This therapy is FDA-approved for cases of depression and obsessive-compulsive disorder (OCD) in cases where pharmaceuticals have proven ineffective (1). Still, research has also shown it to have positive effects in treating anxiety, attention-deficit hyperactivity disorder (ADHD), and borderline personality disorder (BPD).

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ECT, often called “shock therapy,” is a more intense treatment that is used as a last resort. ECT aims to rewire brain circuits by inducing controlled seizures through applying electric currents to the brain. It is used to treat especially severe depression, bipolar disorder, and schizophrenia, typically in emergencies or life-threatening cases.

Why Is ECT A Last Resort?

ECT requires anesthesia and muscle relaxants to prevent bodily harm during seizures. Another primary  concern surrounding ECT is its potential for cognitive side effects, such as memory loss and confusion, which can sometimes be significant (2). Because of these factors and the existence of less severe noninvasive alternatives such as TMS, ETC is generally recommended as a last resort or second-line treatment unless rapid emergency intervention is necessary (for example, a threat of imminent harm or suicide).

ECT’s potential cognitive side effects include memory loss, specifically retrograde amnesia (difficulty recalling past events) and anterograde amnesia (difficulty forming new memories). This can disrupt personal, professional, and social affairs, making it more difficult for the depressed patient to reintegrate into a regular, healthy routine.

Furthermore, ECT is an inpatient procedure that requires hospitalization and the support  of family members, friends, or caregivers to provide transport and care before and after treatment. 

Is ECT More Effective Than TMS?

ECT’s effectiveness is often acknowledged, especially in cases of severe depression where rapid intervention is necessary. In one study of TMS versus ECT for patients with MDD, ECT outperformed TMS on the Hamilton Rating Scale for Depression, reducing symptoms by 15 points as opposed to 9 points for TMS (3). However, TMS has an excellent track record of alleviating symptoms of depression, and the advantages of TMS in terms of safety, convenience, and long-term prospects make it a preferable first option for many patients with treatment-resistant depression.

What Is One Serious Drawback Of Using ECT To Treat Depression?

As well as the potential cognitive side-effects, it should be noted that remission from ECT is often short-term and that in the long term, most patients will require antidepressant medications to manage their symptoms. Antidepressants are not always effective and come with their own side effects, and TMS is a recommended treatment for patients who wish to avoid or reduce dependency on antidepressant drugs.

When Should ECT Not Be Used?

Given the potential risks involved, ECT should not be used if you have:

  • Mild or moderate depression
  • Certain cardiovascular conditions, such as heart attacks, severe hypertension, recent heart attacks or strokes
  • A history of adverse reactions to anesthesia
  • Certain neurological conditions, such as brain tumors or recent head injuries

In all cases, a thorough evaluation of the patient’s condition and the clinical necessity of the treatment should be conducted before ECT is applied.

Which Is Safer, ECT Or TMS?

Unlike ECT, TMS does not induce seizures or require anesthesia or hospitalization, making it less risky and more patient-friendly. Additionally, TMS has fewer cognitive side effects at a much lower risk, meaning patients can often return to their daily activities immediately after a session.

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The precisely targeted nature of TMS means that it will not affect other bodily systems. Although some TMS patients report a mild headache or scalp irritation after a session, these can be easily treated with over-the-counter medications.

How Much Does TMS Cost Compared To ECT?

TMS is less expensive than ECT, as it requires no hospital time and demands fewer resources from medical providers. Although prices vary according to location and a patient’s needs, the average ECT session costs about $2500 compared to a $400-$500 session of TMS. Both therapies may be covered by private insurance or Medicare.

Why Choose TMS Over ECT?

Unless one’s condition is especially severe or life-threatening, most patients prefer TMS over ECT due to its noninvasive nature, cost-effectiveness, and minimal disruption to daily life (4).

Madison Avenue TMS & Psychiatry offers talk therapy and TMS for treating depression, anxiety, and other mental health conditions. Contact us online or call (212) 731-2033 for more information or to make an appointment.


  1. FDA permits marketing of transcranial magnetic stimulation for treatment of obsessive compulsive disorder. U.S. Food & Drug Administration. Updated August 17, 2018. Link. Accessed July 17, 2023.
  2. Porter, R., Baune, B., Morris, G., Hamilton, A., Bassett, D., Boyce, P., . . . Malhi, G. (2020). Cognitive side-effects of electroconvulsive therapy: What are they, how to monitor them and what to tell patients. BJPsych Open. 2020;6(3). Link. Accessed August 14, 2023.  
  3. Micallef-Trigona B (2014). Comparing the effects of repetitive transcranial magnetic stimulation and electroconvulsive therapy in the treatment of depression: a systematic review and meta-analysis. Depression Research and Treatment. 2014. Link. Accessed August 14, 2023.
  4. Magnezi R, Aminov E, Shmuel D, Dreifuss M, Dannon P. Comparison between neurostimulation techniques repetitive transcranial magnetic stimulation vs electroconvulsive therapy for the treatment of resistant depression: patient preference and cost-effectiveness. Patient Prefer Adherence. 2016;10:1481-7. Link. August 14, 2023. 
Dr. Woo has been seeing patients in private practice since 2002, always with the goals of combining evidence-based medicine with psychodynamic psychotherapy and collaborating with other mental health professionals to ensure the best possible outcomes for his patients. He has been certified to administer TMS at his practice since 2017. His greatest clinical interests include helping patients suffering from depression, anxiety, and obsessive compulsive disorder.

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